Coxiella burnetii - Pathogenic Agent of Q (Query) Fever.

نویسندگان

  • Lutz Gürtler
  • Ursula Bauerfeind
  • Johannes Blümel
  • Reinhard Burger
  • Christian Drosten
  • Albrecht Gröner
  • Margarethe Heiden
  • Martin Hildebrandt
  • Bernd Jansen
  • Ruth Offergeld
  • Georg Pauli
  • Rainer Seitz
  • Uwe Schlenkrich
  • Volkmar Schottstedt
  • Johanna Strobel
  • Hannelore Willkommen
چکیده

1.1.1 Structure C. burnetii is a member of the family of the Coxiellaceae bacteria and replicates intracellularly in cells of different species. Phylogenetically related bacteria include Legionellaceae, Francisellaceae, Pseudomonaceae, and other Gammaproteobacteria. Coxiella are small Gram-negative, pleomorphic, coccoid bacteria with a size of 0.2–1.0 m. They occur in 3 different forms: small cells (small cell variant, SCV) which are highly infectious, large cells (large cell variant, LCV) which develop also in cell culture, as well as spore-like particles (SLP) which are infectious and very robust to environmental conditions. Dependent on the host system, Coxiella undergoes a phase variation during growth [12]. In mammalian cells, bacteria grow as LCV, and form spore-like particles and 2 different antigenic forms described as Phase I and II.

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عنوان ژورنال:
  • Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

دوره 41 1  شماره 

صفحات  -

تاریخ انتشار 2014